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Presolol 100 (Labetalol 100 mg) Shortage Update: Substitution Instrument Extended

30 Oct 2025

In response, the Therapeutic Goods (Serious Scarcity and Substitutable Medicine) (Labetalol) Instrument 2025 (SSSI) has been extended to 31 December 2025.

This instrument allows pharmacists to substitute a prescribed labetalol 100 mg tablet with labetalol 200 mg, where clinically appropriate, without requiring a new prescription.

For full details on the shortage and guidance for pharmacists, prescribers, and patients, please visit the About the shortage of Presolol 100 (labetalol hydrochloride 100 mg) tablets page.

Source: Therapeutic Goods Administration